జర్నల్ ఆఫ్ క్లినికల్ అండ్ ఎక్స్పెరిమెంటల్ ఆప్తాల్మాలజీ
అందరికి ప్రవేశం
ISSN: 2155-9570
ISSN: 2155-9570
Perwez Khan, Priyanka Gupta JR, Gupta RC, Shalini Mohan and Lubna Khan
Background: Evaluate final visual outcome, visual recovery time, leakage resolution time on Fundus Angiography (FA), recurrence rate and complications in patients of Central Serous Chorioretinopathy (CSCR) treated with early double frequency Nd-YAG laser photocoagulation as compared to observation alone.
Methods: Prospective, interventional, non-randomized, clinical, comparative trial. Two groups with 15 eyes of CSCR in each group were compared. First group treated with early double frequency Nd-YAG laser and other kept on observation. Best Corrected Visual acuity (BCVA) was recorded at baseline, 2 weeks, 1 month, 2 months and 3 months. FA was done at baseline, 2 weeks and 3 months. Contrast sensitivity was recorded at baseline and at the end of 3 months. Residual metamorphopsia checked at the end of 3 months using Amsler Grid.
Results: BCVA significantly improved in the laser group at the end of 2 weeks (p<0.001). Although at the end of 3 months all 30 eyes had BCVA of 20/30 or better. At baseline all 30 eyes showed leakage on FA. At 2 weeks none of the eye in laser group showed leakage, while all 15 eyes in the observation group showed some amount of leakage. No leakage found in all 30 eyes at 3 months. Contrast sensitivity and residual metamorphopsia was similar in both groups at 3 months. There were no recurrences in the laser group during follow-up of 1 year, while in the observation group 2 eyes had recurrence. None of the eye in the laser group showed any complication related to laser on follow-up.
Conclusions: Early double frequency Nd-YAG laser photocoagulation shortens the time for visual recovery and resolution of leakage on FA in patients of CSCR; is not associated with recurrences or complications but has no effect on the final outcome of quality of vision as compared to observation alone.