జర్నల్ ఆఫ్ క్లినికల్ & ఎక్స్పెరిమెంటల్ డెర్మటాలజీ రీసెర్చ్
అందరికి ప్రవేశం

నైరూప్య

Xeroderma Pigmentosum with Acute Myeloid Leukemia and Meningiomas: Review of Literature

Nadia Zakir Mian, Pragya Kushwaha*

Xeroderma Pigmentosum (XP) a unique disorder, inherited as an autosomal recessive genodermatosis. Characterized by photosensitivity, freckly pigmented changes, premature skin ageing, telegiectasis, warty and papillomatous growth and malignant tumor development in later stage. Results from mutation in seven nucleotide excision repair gene (XPA to XP-G complement groups) and post replication repair defect (XP-Variant). This report aims to acknowledge the unique combination of XP along with neurological defects in a patient of acute myeloid leukemia.