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నైరూప్య

Zika Virus (ZIKV) Infection: A Review

Kunchok Dolma

Zika virus is a mosquito transmitted flavivirus belongs to family Flaviviridae which became the focus of an ongoing pandemic and public health emergency all around the world. It is often misdiagnosed with other disease like Dengue and Chikungunya because of same clinical manifestation. After outbreak of ZIKV infection in Brazil in 2007, a severe neurological complications, Guillain-Barre syndrome and congenital malformations (microcephaly) suspected to be linked with ZIKV. The association between these conditions with Zika virus infection is still not confirmed and is under examination. Since ZIKV has neither an effective treatment nor a vaccine is available, therefore the public health authority focuses on preventing infection, particularly in pregnant women and virus transmitted region. World Health Organization and other health officials are working on the development of new projects and mosquito control methods to cope up with infection as there is very less literature present on the pathogenesis of the Zika virus to help interpret the clinical disease spectrum and target treatments to lessen or prevent infection. WHO/PAHO encourages the countries to establish and maintain Zika virus infection detection, clinical management and community assurance strategies to reduce transmission of the virus. The future status of ZIKV spreading to other parts of the world is still unknown.