ISSN: 2329-9096
Chiara Mega*, Tommaso Tonetti, Alessio Dell’Olio, Marco Vito Ranieri
Clinical outcomes in COVID-19 associated acute respiratory distress syndrome may be influenced by respiratory system mechanics, CT scan findings, oxygenation variables and biomarkers. Low respiratory system compliance and high plasmatic D-dimer were associated to higher mortality rate in a subgroup of COVID-19 patients. Our purpose is to review the impact of respiratory compliance and plasmatic D-dimer in COVID-19 associated acute respiratory distress syndrome according to recent literature. Increased D-dimer concentration in COVID-19 patients is a strong predictor of worse outcome while static respiratory compliance is not. Combined evaluation of both enhances the prediction of mortality in COVID-19 related ARDS.