క్లినికల్ & ప్రయోగాత్మక కార్డియాలజీ
అందరికి ప్రవేశం

నైరూప్య

Coagulation System: New Concepts for Novel Therapeutics

Mohammed Saied Mohammed Bakeer

Our understanding to the process of coagulation is based on the classic coagulation cascade, proposed in 1964 by Macfarlane and Davie & Ratnoff. While is considered to be of clinical validity, still many limitations in this model exist. Drugs for anticoagulation based in this model also show the same limitations of the model. Here we review this model and trying to find new concepts as regard this model, with aiming at finding a new way for developing new drugs for manipulating the coagulation system with more favorable profile.