select ad.sno,ad.journal,ad.title,ad.author_names,ad.abstract,ad.abstractlink,j.j_name,vi.* from articles_data ad left join journals j on j.journal=ad.journal left join vol_issues vi on vi.issue_id_en=ad.issue_id where ad.sno_en='36616' and ad.lang_id='9' and j.lang_id='9' and vi.lang_id='9' Cattle as Experimental Model to Study Immunopathogenesis of | 36616
మైకోబాక్టీరియల్ వ్యాధులు

మైకోబాక్టీరియల్ వ్యాధులు
అందరికి ప్రవేశం

ISSN: 2161-1068

నైరూప్య

Cattle as Experimental Model to Study Immunopathogenesis of Tuberculosis

Promod K Mehta, Renu Dharra and Zoozeal Thakur

Various animal models are used to study the immunology, genetics and molecular biology of Tuberculosis (TB) as well as for testing the new vaccines and drugs. Mice are widely used to study the immunology of chronic TB infection, while guinea pigs are used for aerosol TB infection and rabbits are used to study the lung cavitations. Cattle are natural host to Mycobacterium bovis infection, which act as a connecting link between the small laboratory animals and human counterparts for testing the vaccine efficacy. By using cattle as an experimental model, the disease outcome is understood through natural infection with M. bovis and a comparison can be made with M. tuberculosis infection. In this manuscript, the utility of cattle in understanding the progression of disease and the immunological correlates to evaluate the protective efficacy of vaccines are described.

నిరాకరణ: ఈ సారాంశం కృత్రిమ మేధస్సు సాధనాలను ఉపయోగించి అనువదించబడింది మరియు ఇంకా సమీక్షించబడలేదు లేదా ధృవీకరించబడలేదు.
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