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A Confusing General Term “Frailty” Should be Organized in Relation with Fried’s Criteria for Frailty, Locomotive Syndrome, Musculoskeletal Ambulation Disability Symptom Complex, and Sarcopenia, as Avoiding Fall into “Word Play”

Keiichi Kumai, Kenichi Meguro*

In this review, we organize confusing concepts of frailty, locomotive syndrome, Musculoskeletal Ambulation Disability Symptom (MADS) Complex, and sarcopenia, as avoiding fall into “word play.” The concept of Clinical Dementia Rating may be useful for understanding mixed situations. Clinical conditions differ during the process of lesion development in the brain among patients with Alzheimer disease, and that the idea of biaxial thinking for “disease” and “condition” is required. Regarding frailty, a mix of “disease” and “condition” in criteria may be a cause of confusion, and this may be an important idea in daily clinical practice. Since frailty has been identified as a reason for fall in many academic studies, of which 70% used Fried’s criteria, it is clear that frailty reflects decreased motor function. This suggests a relationship between frailty and fall.