select ad.sno,ad.journal,ad.title,ad.author_names,ad.abstract,ad.abstractlink,j.j_name,vi.* from articles_data ad left join journals j on j.journal=ad.journal left join vol_issues vi on vi.issue_id_en=ad.issue_id where ad.sno_en='6217' and ad.lang_id='9' and j.lang_id='9' and vi.lang_id='9' Controlled Ovarian Hyperstimulation through Gonadotrophin re | 6217
జర్నల్ ఆఫ్ ఫెర్టిలైజేషన్: ఇన్ విట్రో - IVF-వరల్డ్‌వైడ్, రిప్రొడక్టివ్ మెడిసిన్, జెనెటిక్స్ & స్టెమ్ సెల్ బయోల్

జర్నల్ ఆఫ్ ఫెర్టిలైజేషన్: ఇన్ విట్రో - IVF-వరల్డ్‌వైడ్, రిప్రొడక్టివ్ మెడిసిన్, జెనెటిక్స్ & స్టెమ్ సెల్ బయోల్
అందరికి ప్రవేశం

ISSN: 2375-4508

నైరూప్య

Controlled Ovarian Hyperstimulation through Gonadotrophin releasing Hormone Agonist for Patients at Risk of Hyperstimulation Syndrome

Antonio Maselli, Martin Wilding, Sylvia del Grande, Stefania Riccio, Loredana Di Matteo and Brian Dale

Background:Patients at high risk of OHSS can experience difficulty in completing an IVF cycle with the administration of gonadotrophins. Here, we test a unique low-dose GnRH agonist protocol.

Methods: 0.1mg triptorlin acetate (decapeptyl) was administered to 18 patients at high risk of OHSS from day 5 of the menstrual cycle. Oocyte retrieval was performed 36 hours after the administration of 10000 IU human chorionic gonadotrophin, when follicles of 18-20mm were observed. Oocytes were fertilised in vitro and embryos transferred on day 3.

Results: Patients produced a mean of 4.1 ± 0.96 oocytes. After ICSI, a mean of 3.0 ± 0.84 embryos were transferred to the uterus. A total of 5 pregnancies were obtained from the 18 cycles. No patients were affected by OHSS.

Conclusions: Low-dose injections of GnRH analogues can cause multiple follicular development, mature oocytes and pregnancies in patients at risk of OHSS. This novel COH protocol appears safe and applicable as a valuable alternative to the natural cycle.

నిరాకరణ: ఈ సారాంశం కృత్రిమ మేధస్సు సాధనాలను ఉపయోగించి అనువదించబడింది మరియు ఇంకా సమీక్షించబడలేదు లేదా ధృవీకరించబడలేదు.
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